Similarity values obtained by G-SESAME
| | FAA1 | FAA2 | FAA3 | FAA4 | FAT1 | DCI1 | ECI1 | FOX2 | POX1 | POT1 |
| FAA1 | | 1 | 1 | 1 | 0.701 | 0.199 | 0.199 | 0.199 | 0.199 | 0.154 |
| FAA2 | | | 1 | 1 | 0.701 | 0.199 | 0.199 | 0.199 | 0.199 | 0.154 |
| FAA3 | | | | 1 | 0.701 | 0.199 | 0.199 | 0.199 | 0.199 | 0.154 |
| FAA4 | | | | | 0.701 | 0.199 | 0.199 | 0.199 | 0.199 | 0.154 |
| FAT1 | | | | | | 0.168 | 0.168 | 0.176 | 0.168 | 0.130 |
| DCI1 | | | | | | | 1 | 0.199 | 0.199 | 0.154 |
| ECI1 | | | | | | | | 0.199 | 0.199 | 0.154 |
| FOX2 | | | | | | | | | 0.292 | 0.154 |
| POX1 | | | | | | | | | | 0.154 |
| POT1 | | | | | | | | | | |
Clustering results obtained by G-SESAME
| Threshold | Initial | 1.000 | 0.700 | 0.290 | 0.190 | 0.150 |
Clustering
Result |
|
|
|
|
POX1
FOX2
FAA4
FAA3
FAA2
FAA1
FAT1
ECI1
DCI1
|
|
POX1
FOX2
FAA4
FAA3
FAA2
FAA1
FAT1
ECI1
DCI1
POT1
|
|
Similarity values obtained by Resnik's method
| | FAA1 | FAA2 | FAA3 | FAA4 | FAT1 | DCI1 | ECI1 | FOX2 | POX1 | POT1 |
| FAA1 | | 7.568 | 7.568 | 7.568 | 5.045 | 0.281 | 0.281 | 0.281 | 0.281 | 0.281 |
| FAA2 | | | 7.568 | 7.568 | 5.045 | 0.281 | 0.281 | 0.281 | 0.281 | 0.281 |
| FAA3 | | | | 7.568 | 5.045 | 0.281 | 0.281 | 0.281 | 0.281 | 0.281 |
| FAA4 | | | | | 5.045 | 0.281 | 0.281 | 0.281 | 0.281 | 0.281 |
| FAT1 | | | | | | 0.187 | 0.187 | 0.211 | 0.187 | 0.187 |
| DCI1 | | | | | | | 7.871 | 0.281 | 0.281 | 0.281 |
| ECI1 | | | | | | | | 0.281 | 0.281 | 0.281 |
| FOX2 | | | | | | | | | 1.013 | 0.281 |
| POX1 | | | | | | | | | | 0.281 |
| POT1 | | | | | | | | | | |
Clustering results obtained by Resnik's method
| Threshold | Initial | 7.872 | 7.472 | 4.972 | 0.972 | 0.272 |
Clustering
Result |
|
|
|
|
|
POX1
FOX2
FAA4
FAA3
FAA2
FAA1
FAT1
ECI1
DCI1
POT1
|
|
Analysis:
Genes DCI1 and ECI1 are annotated by the same molecular function term GO:0004165: dodecenoyl-CoA delta-isomerase activity.
Genes FAA1, FAA2, FAA3 and FAA4 are annotated by the same molecular function term GO:0004467: long-chain-fatty-acid-CoA ligase activity.
Therefore, genes DCI1 and ECI have the same molecular function.
Genes FAA1, FAA2, FAA3 and FAA4 have the same molecular function.
The similarity values and clustering results obtained by G-SESAME are consistent with these observations.
However, based on Resnik's method, the similarity between DCI1 and ECI1 is greater than
the similarity among FAA1, FAA2, FAA3 and FAA4, inconsistent with the observations.
Conclusion:
G-SESAME is better.