45. glycerol biosynthesis

Similarity values obtained by G-SESAME

  TGL1 TGL2 ATG15
TGL1  0.7900.909
TGL2    0.869
ATG15     

Clustering results obtained by G-SESAME

Threshold Initial0.9000.860
Clustering
Result
ATG15

TGL1

TGL2

ATG15
TGL1

TGL2

ATG15
TGL1
TGL2

Similarity values obtained by Resnik's method

  TGL1 TGL2 ATG15
TGL1   4.7324.732
TGL2     5.226
ATG15      

Clustering results obtained by Resnik's method

Threshold Initial5.2264.726
Clustering
Result
ATG15

TGL2

TGL1

ATG15
TGL2

TGL1

ATG15
TGL2
TGL1

Annotation information for ATG15 and TGL1:

Yellow term annotates both genes ATG15 and TGL1. Green term annotates gene TGL1.

Annotation information for ATG15 and TGL2:

Red term annotates gene ATG15. Green term annotates gene TGL2.

Analysis:

The annotation information for TGL1, TGL2 and ATG15 in the above figures shows that term GO:0016298 annotates both genes TGL1 and ATG15. On the other hand, GO:0004806 which annotates gene TGL2 is a child term of GO:0016298.

Because the similarity value between ATG15 and TGL1 is so close to the similarity value between ATG15 and TGL2, it is hard to determine which method provides a better measurement based on the annotation information.

Conclusion:

Both methods are equal.