Similarity values obtained by G-SESAME
| | AAT1 | AAT2 | ASN1 | ASN2 |
| AAT1 | | 1 | 0.199 | 0.199 |
| AAT2 | | | 0.199 | 0.199 |
| ASN1 | | | | 1 |
| ASN2 | | | | |
Clustering results obtained by G-SESAME
| Threshold | Initial | 1.000 | 0.190 |
Clustering
Result |
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Similarity values obtained by Resnik's method
| | AAT1 | AAT2 | ASN1 | ASN2 |
| AAT1 | | 6.059 | 0.281 | 0.281 |
| AAT2 | | | 0.281 | 0.281 |
| ASN1 | | | | 6.703 |
| ASN2 | | | | |
Clustering results obtained by Resnik's method
| Threshold | Initial | 6.704 | 6.004 | 0.204 |
Clustering
Result |
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Analysis:
Genes AAT1 and AAT2 are annotated by the same molecular function term GO:0004069: aspartate transaminase activity.
Genes ASN1 and ASN2 are annotated by the same molecular function term GO:0004066: asparagine synthase (glutamine-hydrolyzing) activity.
Therefore, genesAAT1 and AAT2 have the same molecular function.
Genes ASN1 and ASN2 have the same molecular function.
The similarity values and clustering results obtained by G-SESAME are consistent with these observations.
However, based on Resnik's method, the similarity between ASN1 and ASN2 is greater than
the similarity between DCI1 and ECI, inconsistent with the observations.
Conclusion:
G-SESAME is better.